姓 名:易浩安
出生年月:1995年10月
硕导/博导:硕士研究生导师
学 位:博士研究生
所属科室:基础医学院 细胞生物学与医学遗传学系
职 务:无
所获奖项:无
招生专业:细胞生物学
研究领域:免疫代谢、遗传进化
社会兼职:无
其他介绍:无
主持或参加科研项目及人才计划项目情况(按时间倒序排序):
1.国家自然科学基金地区基金项目,82560402,G6PD缺乏症通过SYK/STAT1通路调控CD4+T细胞分化介导脑型疟疾抗性的机制研究,2026/01-2029/12,32万元,在研,主持。
2.云南省科技厅-昆明医科大学联合专项,202501AY070001-151,G6PD调控CXCR3+CD8+T细胞趋化在脑型疟疾中的作用和机制研究,2025/05 -2028/04,在研,主持。
3.云南省科技厅基础研究计划,202401AU070068,G6PD缺乏症调控CD8+T细胞GranzymeB表达在脑型疟疾中的作用及机制,2024/03-2027/02,在研,主持。
代表性成果:
期刊论文:
1. Zhang, X#, J. Wu#, Y. Peng, L. Luo, L. Zhang, X. Huang, G. Chen, Y. Li* and H. Yi* (2025). Human genetic variations conferring resistance to malaria. J Transl Med 23(1): 997.
2. Yi, H#, Y. Jiang#, W. Li, L. Shen, W. Zhang, S. Li*, Y. Xu* and F. Li * (2025). Scutellarin prevents obesity-induced renal fibrosis via reduced activation of AP-1. J Transl Med 23(1): 611.
3. Kong, Y#, H. Yi#, F. Li, X. Duan, L. Yang, X. Fan, G. Wu, M. Ma, X. Zha* and Y. He* (2023). A novel missense mutation in the CRYBA2 caused autosomal dominant presenile cataract in a Chinese family. Mol Genet Genomics 298(5): 1237-1244.
4. Yi, H#, C. Liu#, J. Shi, S. Wang, H. Zhang, Y. He, J. Tao, S. Li* and R. Zhang* (2022). EGCG Alleviates Obesity-Induced Myocardial Fibrosis in Rats by Enhancing Expression of SCN5A. Front Cardiovasc Med 9: 869279.
5. Yi, H#, W. Jiang#, F. Yang, F. Li, Y. Li, W. Zhu, Q. Li, S. H. Fakhar, Y. Cao, L. Luo, W. Zhang and Y. He* (2021). G6pd-Deficient Mice Are Protected From Experimental Cerebral Malaria and Liver Injury by Suppressing Proinflammatory Response in the Early Stage of Plasmodium berghei Infection. Front Immunol 12: 719189.
6. Gu, D #, H. Yi#, K. Jiang, S. H. Fakhar, J. Shi, Y. He, B. Liu, Y. Guo*, X. Fan* and S. Li* (2021). Transcriptome analysis reveals the efficacy of ginsenoside-Rg1 in the treatment of nonalcoholic fatty liver disease. Life Sci 267: 118986.
7. Yi, H#, H. Li#, L. Liang, Y. Wu, L. Zhang, W. Qiu, W. Jiang, F. Yang, Q. Li, Z. Yang, C. Wang, L. Cui* and Y. He* (2019). The glucose-6-phosphate dehydrogenase Mahidol variant protects against uncomplicated Plasmodium vivax infection and reduces disease severity in a Kachin population from northeast Myanmar. Infect Genet Evol 75: 103980.
8. Yi, H#, X. Zha#, Y. Zhu, J. Lv, S. Hu, Y. Kong, G. Wu, Y. Yang and Y. He* (2019). A novel nonsense mutation in ADAMTS17 caused autosomal recessive inheritance Weill-Marchesani syndrome from a Chinese family. J Hum Genet 64(7): 681-687.
9. Deng, Z#, Q. Li, # H. Yi#, Y. Zhang, F. Yang, H. Li, L. Luo, L. Ma, Z. Yang, Y. He* and L. Cui* (2018). Hemoglobin E protects against acute Plasmodium vivax infections in a Kachin population at the China-Myanmar border. J Infect 77(5): 435-439.